Glycemia and cognitive function in metabolic syndrome and coronary heart disease.

ABSTRACT:

Objective

Higher hemoglobin A1c (HbA1c) is associated with lower cognitive function in type 2 diabetes. To determine whether associations persist at lower levels of dysglycemia in patients who have established cardiovascular disease, cognitive performance was assessed in the Targeting INflammation Using SALsalate in CardioVascular Disease (TINSAL-CVD) trial.

Methods

The age-adjusted relationships between HbA1c and cognitive performance measured by the Mini-Mental State Examination, Digit Symbol Substitution Test, Rey Auditory Verbal Learning Test, Trail Making Test, and Categorical Verbal Fluency were assessed in 226 men with metabolic syndrome and established stable coronary artery disease.

Results

Of the participants, 61.5% had normoglycemia, 20.8% had impaired fast

SUBMITTER: Avadhani R 

PROVIDER: S-EPMC4306431 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature