Outcomes of eyes with lesions composed of >50% blood in the Comparison of Age-related Macular Degeneration Treatments Trials (CATT).

ABSTRACT:

Objective

To compare baseline characteristics, treatment frequency, visual acuity (VA), and morphologic outcomes of eyes with >50% of the lesion composed of blood (B50 group) versus all other eyes (Other group) enrolled in the Comparison of Age-Related Macular Degeneration Treatments Trials (CATT).

Design

Prospective cohort study within a multicenter randomized clinical trial.

Participants

CATT patients with neovascular age-related macular degeneration (AMD).

Methods

Treatment for the study eye was assigned randomly to either ranibizumab or bevacizumab and to 3 different dosing regimens over a 2-year period. Reading center graders evaluated baseline and follow-up morphology in color fundus photographs, fluorescein angiography (FA), and optical coherence tomogra

SUBMITTER: Altaweel MM 

PROVIDER: S-EPMC4306628 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature