Viral etiologies of acute dehydrating gastroenteritis in pakistani children: confounding role of parechoviruses.

ABSTRACT: Despite substantial interventions in the understanding and case management of acute gastroenteritis, diarrheal diseases are still responsible for a notable amount of childhood deaths. Although the rotavirus is known to cause a considerable burden of pediatric diarrheal cases, the roles of other viruses remain undefined for the Pakistani population. This study was based on tertiary care hospital surveillance, from January 2009 to December 2010, including the detection of rotavirus, norovirus, astrovirus, and human parechovirus in children under the age of five using serological or molecular assays. Rotavirus, human parechovirus, norovirus, and astrovirus were detected in 66%, 21%, 19.5%, and 8.5% subjects, respectively. Human parechovirus genotypes, determined through analysis of VP1 gene s

SUBMITTER: Alam MM 

PROVIDER: S-EPMC4306844 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature