Sulfated galactofucan from the brown alga Saccharina latissima--variability of yield, structural composition and bioactivity.

ABSTRACT: The fucose-containing sulfated polysaccharides (SP) from brown algae exhibit a wide range of bioactivities and are, therefore, considered promising candidates for health-supporting and medicinal applications. A critical issue is their availability in high, reproducible quality. The aim of the present study was to fractionate and characterize the SP extracted from Saccharina latissima (S.l.-SP) harvested from two marine habitats, the Baltic Sea and North Atlantic Ocean, in May, June and September. The fractionation of crude S.l.-SP by anion exchange chromatography including analytical investigations revealed that S.l.-SP is composed of a homogeneous fraction of sulfated galactofucan (SGF) and a mixture of low-sulfated, uronic acid and protein containing heteropolysaccharides. Furthermore, t

SUBMITTER: Ehrig K 

PROVIDER: S-EPMC4306926 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature