Visceral adiposity is negatively associated with bone density and muscle attenuation.

ABSTRACT:

Background

The storage of adipose tissue in ectopic compartments is a hallmark attribute linking greater body mass index (BMI) with cardiometabolic diseases. Despite ample evidence to confirm that increased visceral adipose tissue (VAT) deposition occurs with obesity, the interrelations between altered fat partitioning and regional muscle and bone quality are less well understood.

Objective

We examined the association between adiposity and spinal muscle and bone quality across a large, heterogeneous cohort of adults.

Design

We identified 8833 thoracic or abdominal computed tomography scans from patients in the University of Michigan Health System who were aged 18-64.9 y. We measured trabecular bone densities, cortical bone densities, VAT areas, and subcutaneous adipos

SUBMITTER: Zhang P 

PROVIDER: S-EPMC4307204 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature