Expression and clinical significance of c-Met in advanced esophageal squamous cell carcinoma.

ABSTRACT:

Background

c-Met, one of current potential hot targets, has been suggested as a potential tumor marker in the development of esophageal squamous cell carcinoma (ESCC). Our aim was to investigate the expression of c-Met in advanced esophageal squamous cell carcinoma in four phase II trials who had tumor tissues from archival in our center and analyze the correlations between c-Met expression and clinical features.

Methods

Ninety patients with advanced ESCC who were admitted to the phase II clinical trials in the Department of Gastrointestinal Oncology, Peking University Cancer Hospital and Institute from March 2007 to March 2014 were finally eligible for present study and the corresponding tissues and clinical data were collected. The expression of c-Met in the tissue samples

SUBMITTER: Xu Y 

PROVIDER: S-EPMC4307685 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature