Feasibility and validity of the pediatric ulcerative colitis activity index in routine clinical practice.

ABSTRACT:

Objectives

The Pediatric Ulcerative Colitis Activity Index (PUCAI) is a noninvasive disease activity index developed as a clinical trial endpoint. More recently, practice guidelines have recommended the use of PUCAI in routine clinical care. We therefore sought to evaluate the feasibility, validity, and responsiveness of PUCAI in a large, diverse collection of pediatric gastroenterology practices.

Methods

We extracted data from the 2 most recent encounters for patients with ulcerative colitis in the ImproveCareNow registry. Feasibility was determined by the percentage of patients for whom all PUCAI components were recorded, validity by correlation of PUCAI scores across physician global assessment (PGA) categories, and responsiveness to change by the correlation between the

SUBMITTER: Dotson JL 

PROVIDER: S-EPMC4308561 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature