Comparing human-Salmonella with plant-Salmonella protein-protein interaction predictions.

ABSTRACT: Salmonellosis is the most frequent foodborne disease worldwide and can be transmitted to humans by a variety of routes, especially via animal and plant products. Salmonella bacteria are believed to use not only animal and human but also plant hosts despite their evolutionary distance. This raises the question if Salmonella employs similar mechanisms in infection of these diverse hosts. Given that most of our understanding comes from its interaction with human hosts, we investigate here to what degree knowledge of Salmonella-human interactions can be transferred to the Salmonella-plant system. Reviewed are recent publications on analysis and prediction of Salmonella-host interactomes. Putative protein-protein interactions (PPIs) between Salmonella and its human and Arabidopsis hosts were re

SUBMITTER: Schleker S 

PROVIDER: S-EPMC4309195 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature