Rates of retinal nerve fiber layer thinning in glaucoma suspect eyes.

ABSTRACT:

Purpose

To compare the rates of retinal nerve fiber layer (RNFL) loss in patients suspected of having glaucoma who developed visual field damage (VFD) with those who did not develop VFD and to determine whether the rate of RNFL loss can be used to predict the development of VFD.

Design

Prospective, observational cohort study.

Participants

Glaucoma suspects, defined as having glaucomatous optic neuropathy or ocular hypertension (intraocular pressure, >21 mmHg) without repeatable VFD at baseline, from the Diagnostic Innovations in Glaucoma Study and the African Descent and Glaucoma Evaluation Study.

Methods

Global and quadrant RNFL thickness (RNFLT) were measured with the Spectralis spectral-domain optical coherence tomography (SD-OCT; Spectralis HRA+OCT [Heidelb

SUBMITTER: Miki A 

PROVIDER: S-EPMC4310561 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature