Temporal-spatial correlation between angiogenesis and corticogenesis in the developing chick optic tectum.

ABSTRACT: The developing chick optic tectum is a widely used model of corticogenesis and angiogenesis. Cell behaviors involved in corticogenesis and angiogenesis share several regulatory mechanisms. In this way the 3D organizations of both systems adapt to each other. The consensus about the temporally and spatially organized progression of the optic tectum corticogenesis contrasts with the discrepancies about the spatial organization of its vascular bed as a function of the time. In order to find out spatial and temporal correlations between corticogenesis and angiogenesis, several methodological approaches were applied to analyze the dynamic of angiogenesis in the developing chick optic tectum. The present paper shows that a typical sequence of developmental events characterizes the optic tectum a

SUBMITTER: Rodriguez Celin A 

PROVIDER: S-EPMC4310613 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature