Microarray-based detection of viruses causing vesicular or vesicular-like lesions in livestock animals.

ABSTRACT: Definitive diagnosis of vesicular or vesicular-like lesions in livestock animals presents challenges both for veterinary clinicians and diagnostic laboratories. It is often impossible to diagnose the causative disease agent on a clinical basis alone and difficult to collect ample vesicular epithelium samples. Due to restrictions of time and sample size, once laboratory tests have ruled out foot-and-mouth disease, vesicular stomatitis and swine vesicular disease a definitive diagnosis may remain elusive. With the ability to test a small quantity of sample for a large number of pathogens simultaneously, DNA microarrays represent a potential solution to this problem. This study describes the application of a long oligonucleotide microarray assay to the identification of viruses known to cause

SUBMITTER: Jack PJ 

PROVIDER: S-EPMC4310687 | biostudies-literature | 2009 Jan

REPOSITORIES: biostudies-literature