Associations between self-referral and health behavior responses to genetic risk information.

ABSTRACT:

Background

Studies examining whether genetic risk information about common, complex diseases can motivate individuals to improve health behaviors and advance planning have shown mixed results. Examining the influence of different study recruitment strategies may help reconcile inconsistencies.

Methods

Secondary analyses were conducted on data from the REVEAL study, a series of randomized clinical trials examining the impact of genetic susceptibility testing for Alzheimer's disease (AD). We tested whether self-referred participants (SRPs) were more likely than actively recruited participants (ARPs) to report health behavior and advance planning changes after AD risk and APOE genotype disclosure.

Results

Of 795 participants with known recruitment status, 546 (69%) were

SUBMITTER: Christensen KD 

PROVIDER: S-EPMC4311425 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature