Multiaddressable molecular rectangles with reversible host-guest interactions: modulation of pH-controlled guest release and capture.

ABSTRACT: A series of multiaddressable platinum(II) molecular rectangles with different rigidities and cavity sizes has been synthesized by endcapping the U-shaped diplatinum(II) terpyridine moiety with various bis-alkynyl ligands. The studies of the host-guest association with various square planar platinum(II), palladium(II), and gold(III) complexes and the related low-dimensional gold(I) complexes, most of which are potential anticancer therapeutics, have been performed. Excellent guest confinement and selectivity of the rectangular architecture have been shown. Introduction of pH-responsive functionalities to the ligand backbone generates multifunctional molecular rectangles that exhibit reversible guest release and capture on the addition of acids and bases, indicating their potential in contro

SUBMITTER: Chan AK 

PROVIDER: S-EPMC4311808 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature