Insights into the origin of rare haplogroup C3* Y chromosomes in South America from high-density autosomal SNP genotyping.

ABSTRACT: The colonization of Americas is thought to have occurred 15-20 thousand years ago (Kya), with little or no subsequent migration into South America until the European expansions beginning 0.5 Kya. Recently, however, haplogroup C3* Y chromosomes were discovered in two nearby Native American populations from Ecuador. Since this haplogroup is otherwise nearly absent from the Americas but is common in East Asia, and an archaeological link between Ecuador and Japan is known from 6 Kya, an additional migration 6 Kya was suggested. Here, we have generated high-density autosomal SNP genotypes from the Ecuadorian populations and compared them with genotypes from East Asia and elsewhere to evaluate three hypotheses: a recent migration from Japan, a single pulse of migration from Japan 6 Kya, and no m

SUBMITTER: Mezzavilla M 

PROVIDER: S-EPMC4312352 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature