Invasive mycosis due to species of Blastobotrys in immunocompromised patients with reduced susceptibility to antifungals.

ABSTRACT: Cases of invasive mycosis due to Blastobotrys serpentis and B. proliferans identified by sequencing in a preterm patient and a rhabdomyosarcoma patient, respectively, are reported. Both species revealed elevated fluconazole and echinocandin MICs by the CLSI broth microdilution method. Additionally, B. serpentis exhibited high amphotericin B MICs, thus posing serious therapeutic challenges.

SUBMITTER: Kumar A 

PROVIDER: S-EPMC4313262 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature