Comparative analysis of African swine fever virus genotypes and serogroups.

ABSTRACT: African swine fever virus (ASFV) causes highly lethal hemorrhagic disease among pigs, and ASFV's extreme antigenic diversity hinders vaccine development. We show that p72 ASFV phylogenetic analysis does not accurately define ASFV hemadsorption inhibition assay serogroups. Thus, conventional ASFV genotyping cannot discriminate between viruses of different virulence or predict efficacy of a specific ASFV vaccine.

SUBMITTER: Malogolovkin A 

PROVIDER: S-EPMC4313636 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature