SNPs in PTGS2 and LTA predict pain and quality of life in long term lung cancer survivors.

ABSTRACT:

Purpose

Lung cancer survivors report the lowest quality of life relative to other cancer survivors. Pain is one of the most devastating, persistent, and incapacitating symptoms for lung cancer survivors. Prevalence rates vary with 80-100% of survivors experiencing cancer pain and healthcare costs are five times higher in cancer survivors with uncontrolled pain. Cancer pain often has a considerable impact on quality of life among cancer patients and cancer survivors. Therefore, early identification, and treatment is important. Although recent studies have suggested a relationship between single nucleotide polymorphisms (SNPs) in several cytokine and inflammation genes with cancer prognosis, associations with cancer pain are not clear. Therefore, the primary aim of this study was to

SUBMITTER: Rausch SM 

PROVIDER: S-EPMC4314090 | biostudies-literature | 2012 Jul

REPOSITORIES: biostudies-literature