Pleiotropic locus for emotion recognition and amygdala volume identified using univariate and bivariate linkage.

ABSTRACT:

Objective

The role of the amygdala in emotion recognition is well established, and amygdala volume and emotion recognition performance have each been shown separately to be highly heritable traits, but the potential role of common genetic influences on both traits has not been explored. The authors investigated the pleiotropic influences of amygdala volume and emotion recognition performance.

Method

In a sample of randomly selected extended pedigrees (N=858), the authors used a combination of univariate and bivariate linkage to investigate pleiotropy between amygdala volume and emotion recognition performance and followed up with association analysis.

Results

The authors found a pleiotropic region for amygdala volume and emotion recognition performance on chromosome 4

SUBMITTER: Knowles EE 

PROVIDER: S-EPMC4314438 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature