Cortical and trabecular bone in pediatric end-stage kidney disease.

ABSTRACT: Cortical bone represents nearly 80 % of human bone mass and is the major determinant of bone strength; however, cortical bone parameters and their relationship to trabecular bone in the pediatric chronic kidney disease (CKD) population have not been evaluated.Biochemical values and cortical and trabecular bone parameters were assessed in 22 pediatric dialysis patients: 12 with high and 10 with normal to low trabecular bone turnover.Trabecular bone turnover and osteoid volume correlated with parathyroid hormone (PTH) levels (r?=?0.86, p?

SUBMITTER: Carvalho CG 

PROVIDER: S-EPMC4315739 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature