The contribution of primary prevention medication and dietary change in coronary mortality reduction in England between 2000 and 2007: a modelling study.

ABSTRACT:

Objective

To analyse the falls in coronary heart disease (CHD) mortality in England between 2000 and 2007 and quantify the relative contributions from preventive medications and population-wide changes in blood pressure (BP) and cholesterol levels, particularly by exploring socioeconomic inequalities.

Design

A modelling study.

Setting

Sources of data included controlled trials and meta-analyses, national surveys and official statistics.

Participants

English population aged 25+ in 2000-2007.

Main outcome measures

Number of deaths prevented or postponed (DPPs) in 2007 by socioeconomic status. We used the IMPACTSEC model which applies the relative risk reduction quantified in previous randomised controlled trials and meta-analyses to partition the mortality

SUBMITTER: Guzman-Castillo M 

PROVIDER: S-EPMC4316419 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature