Is schizophrenia associated with an increased risk of chronic kidney disease? A nationwide matched-cohort study.

ABSTRACT:

Objective

The impact of schizophrenia on vital diseases, such as chronic kidney disease (CKD), has not as yet been verified. This study aims to establish whether there is an association between schizophrenia and CKD.

Design

A nationwide matched cohort study.

Setting

Taiwan's National Health Insurance Research Database.

Participants

A total of 2338 patients with schizophrenia, and 7014 controls without schizophrenia (1:3), matched cohort for sex, age group, geography, urbanisation and monthly income, between 1 January 2003 and 31 December 2007, based on the International Classifications of Disease Ninth Edition (ICD-9), Clinical Modification codes.

Primary and secondary outcome measures

After making adjustments for confounding risk factors, a Cox proporti

SUBMITTER: Tzeng NS 

PROVIDER: S-EPMC4316552 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature