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Solid phase synthesis of hydrogen bond surrogate derived alpha-helices: resolving the case of a difficult amide coupling.


ABSTRACT: Solid phase synthesis of HBS helices involving the Fukuyama-Mitsunobu reaction and triphosgene coupling is described.

SUBMITTER: Patgiri A 

PROVIDER: S-EPMC4317285 | biostudies-literature | 2010 Apr

REPOSITORIES: biostudies-literature