Pulp and plaque microbiotas of children with severe early childhood caries.

ABSTRACT:

Background and objective

Bacterial invasion into pulps of primary teeth can lead to infection and premature tooth loss in children. This pilot study aimed to explore whether the microbiota of carious exposures of dental pulps resembles that of carious dentin or that of infected root canals.

Design

Children with severe early childhood caries were studied. Children were consented and extent of caries, plaque, and gingivitis measured. Bacteria were sampled from carious lesion biofilms and vital carious exposures of pulps, and processed by anaerobic culture. Isolates were characterized from partial sequences of the 16S rRNA gene and identified by comparison with taxa in the Human Oral Microbiome Database (http://www.HOMD.org). The microbiotas of carious lesions and dental pulps

SUBMITTER: Chalmers NI 

PROVIDER: S-EPMC4317471 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature