Global nucleosome positioning regulates salicylic acid mediated transcription in Arabidopsis thaliana.

ABSTRACT:

Background

The nucleosome positioning regulates the gene expression and many other DNA-related processes in eukaryotes. Genome-wide mapping of nucleosome positions and correlation of genome-wide nucleosomal remodeling with the changes in the gene expression can help us understanding gene regulation on genome level.

Results

In the present study, we correlate the gene expression and the genomic nucleosomal remodeling in response to salicylic acid (SA) treatment in A. thaliana. We have mapped genome-wide nucleosomes by performing tiling microarray using 146 bp mononucleosomal template DNA. The average nucleosomal coverage is approximately 346 bp per nucleosome both under the control and the SA-treated conditions. The nucleosomal coverage is more in the coding region than in the

SUBMITTER: Singh M 

PROVIDER: S-EPMC4318435 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature