Association of endogenous sex hormones with adipokines and ghrelin in postmenopausal women.

ABSTRACT:

Context

Sex hormones, adipokines, and ghrelin have been implicated in central control of appetite, energy homeostasis, maintenance of fat mass, and inflammation. Women tend to gain weight after menopause and adipose tissue is a major source of sex steroid postmenopause. Understanding the dynamics of these analytes are of particular importance in postmenopausal women, who are at greater risk for cardiometabolic diseases.

Objectives

This study sought to evaluate the associations of adipokines and ghrelin with sex hormone concentrations in postmenopausal women.

Design

We conducted a cross-sectional analysis of baseline clinical trial data.

Setting

The parent trial was conducted at a university clinical research facility.

Participants

Baseline data from 634

SUBMITTER: Karim R 

PROVIDER: S-EPMC4318897 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature