Increasing complexity of clinical research in gastroenterology: implications for the training of clinician-scientists.

ABSTRACT:

Objectives

Significant advances have been made in clinical and epidemiologic research methods over the past 30 years. We sought to demonstrate the impact of these advances on published gastroenterology research from 1980 to 2010.

Methods

Twenty original clinical articles were randomly selected from each of three journals from 1980, 1990, 2000, and 2010. Each article was assessed for topic, whether the outcome was clinical or physiologic, study design, sample size, number of authors and centers collaborating, reporting of various statistical methods, and external funding.

Results

From 1980 to 2010, there was a significant increase in analytic studies, clinical outcomes, number of authors per article, multicenter collaboration, sample size, and external funding. There w

SUBMITTER: Scott FI 

PROVIDER: S-EPMC4319319 | biostudies-literature | 2012 Apr

REPOSITORIES: biostudies-literature