Classifying genotype F of hepatitis B virus into F1 and F2 subtypes.

ABSTRACT:

Aim

To explore the propriety of providing hepatitis B virus (HBV) genotypes F and H with two distinct genotypes.

Methods

Eleven HBV isolates of genotype F (HBV/F) were recovered from patients living in San Francisco, Japan, Panama, and Venezuela, and their full-length sequences were determined. Phylogenetic analysis was carried out among them along with HBV isolates previously reported.

Results

Seven of them clustered with reported HBV/F isolates in the phylogenetic tree constructed on the entire genomic sequence. The remaining four flocked on another branch along with three HBV isolates formerly reported as genotype H. These seven HBV isolates, including the four in this study and the three reported, had a sequence divergence of 7.3-9.5% from the other HBV/F isolates

SUBMITTER: Kato H 

PROVIDER: S-EPMC4320333 | biostudies-literature | 2005 Oct

REPOSITORIES: biostudies-literature