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Spiroguanidine rhodamines as fluorogenic probes for lysophosphatidic acid.


ABSTRACT: Direct determination of total lysophosphatidic acid (LPA) was accomplished using newly developed spiroguanidines derived from rhodamine B as universal fluorogenic probes. Optimum conditions for the quantitative analysis of total LPA were investigated. The linear range for the determination of total LPA is up to 5 μM with a limit of detection of 0.512 μM.

SUBMITTER: Wang L 

PROVIDER: S-EPMC4320994 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature