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Long-term follow-up after bronchoscopic lung volume reduction treatment with coils in patients with severe emphysema.


ABSTRACT:

Background and objective

Bronchoscopic lung volume reduction coil (LVR-coil) treatment has been shown to be safe and clinically effective in patients with severe emphysema in the short term; however, long-term safety and effectiveness has not been evaluated. The aim of this study was to investigate the long-term safety and effectiveness of LVR-coil treatment in patients with severe emphysema.

Methods

Thirty-eight patients with severe emphysema (median age is 59 years, forced expiratory volume in 1 s is 27% predicted) who were treated in LVR-coil clinical trials were invited for a voluntary annual visit. Safety was evaluated by chest X-ray and recording of adverse events and by efficacy by pulmonary function testing, 6-min walk distance (6MWD) and questionnaires.

Results</

SUBMITTER: Hartman JE 

PROVIDER: S-EPMC4321042 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature