Fear and C-reactive protein cosynergize annual pulse increases in healthy adults.

ABSTRACT: Recent international terror outbreaks notably involve long-term mental health risks to the exposed population, but whether physical health risks are also anticipated has remained unknown. Here, we report fear of terror-induced annual increases in resting heart rate (pulse), a notable risk factor of all-cause mortality. Partial least squares analysis based on 325 measured parameters successfully predicted annual pulse increases, inverse to the expected age-related pulse decline, in approximately 4.1% of a cohort of 17,380 apparently healthy active Israeli adults. Nonbiased hierarchical regression analysis among 27 of those parameters identified pertinent fear of terror combined with the inflammatory biomarker C-reactive protein as prominent coregulators of the observed annual pulse increase

SUBMITTER: Shenhar-Tsarfaty S 

PROVIDER: S-EPMC4321278 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature