Adverse effects of maternal lead levels on birth outcomes in the ALSPAC study: a prospective birth cohort study.

ABSTRACT:

Objective

To study the associations of prenatal blood lead levels (B-Pb) with pregnancy outcomes in a large cohort of mother-child pairs in the UK.

Design

Prospective birth cohort study.

Setting

Avon area of Bristol, UK.

Population

Pregnant women enrolled in the Avon Longitudinal Study of Parents and Children (ALSPAC).

Methods

Whole blood samples were collected and analysed by inductively coupled plasma dynamic reaction cell mass spectrometry (n = 4285). Data collected on the infants included anthropometric variables and gestational age at delivery. Linear regression models for continuous outcomes and logistic regression models for categorical outcomes were adjusted for covariates including maternal height, smoking, parity, sex of the baby and gestationa

SUBMITTER: Taylor CM 

PROVIDER: S-EPMC4322474 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature