Ischemic brain lesions after carotid artery stenting increase future cerebrovascular risk.

ABSTRACT:

Background

Brain lesions on diffusion-weighted imaging (DWI) are frequently found after carotid artery stenting (CAS), but their clinical relevance remains unclear.

Objectives

This study sought to investigate whether periprocedural ischemic DWI lesions after CAS or carotid endarterectomy (CEA) are associated with an increased risk of recurrent cerebrovascular events.

Methods

In the magnetic resonance imaging (MRI) substudy of ICSS (International Carotid Stenting Study), 231 patients with symptomatic carotid stenosis were randomized to undergo CAS (n=124) or CEA (n=107). MRIs were performed 1 to 7 days before and 1 to 3 days after treatment. The primary outcome event was stroke or transient ischemic attack in any territory occurring between the post-treatment MRI and t

SUBMITTER: Gensicke H 

PROVIDER: S-EPMC4323145 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature