Changes in the equine fecal microbiota associated with the use of systemic antimicrobial drugs.

ABSTRACT:

Background

The intestinal tract is a rich and complex environment and its microbiota has been shown to have an important role in health and disease in the host. Several factors can cause disruption of the normal intestinal microbiota, including antimicrobial therapy, which is an important cause of diarrhea in horses. This study aimed to characterize changes in the fecal bacterial populations of healthy horses associated with the administration of frequently used antimicrobial drugs.

Results

Twenty-four adult mares were assigned to receive procaine penicillin intramuscularly (IM), ceftiofur sodium IM, trimethoprim sulfadiazine (TMS) orally or to a control group. Treatment was given for 5 consecutive days and fecal samples were collected before drug administration (Day 1), at

SUBMITTER: Costa MC 

PROVIDER: S-EPMC4323147 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature