Kinematic measurement of 12-week head control correlates with 12-month neurodevelopment in preterm infants.

ABSTRACT:

Background

Although new interventions treating neonatal brain injury show great promise, our current ability to predict clinical functional outcomes is poor. Quantitative biomarkers of long-term neurodevelopmental outcome are critically needed to gauge treatment efficacy. Kinematic measures derived from commonly used developmental tasks may serve as early objective markers of future motor outcomes.

Aim

To develop reliable kinematic markers of head control at 12week corrected gestational age (CGA) from two motor tasks: head lifting in prone and pull-to-sit.

Study design and subjects

Prospective observational study of 22 preterm infants born between 24 and 34weeks of gestation.

Outcome measures

Bayley Scales of Infant Development III (Bayley) motor scores.

Res

SUBMITTER: Bentzley JP 

PROVIDER: S-EPMC4324091 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature