Rates of pneumococcal disease in adults with chronic medical conditions.

ABSTRACT:

Background

Although it is widely accepted that adults with immunocompromising conditions are at greatly increased risk of pneumococcal infection, the extent of risk among immunocompetent adults with chronic medical conditions is less certain, particularly in the current era of universal vaccination of children with pneumococcal conjugate vaccines.

Methods

We conducted a retrospective cohort study using data from 3 healthcare claims repositories (2006-2010) to compare rates of pneumococcal disease in immunocompetent adults with chronic medical conditions ("at-risk") and immunocompromised adults ("high-risk"), with rates in adults without these conditions ("healthy"). Risk profiles and episodes of pneumococcal disease-all-cause pneumonia, pneumococcal pneumonia, and invasive p

SUBMITTER: Shea KM 

PROVIDER: S-EPMC4324183 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature