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Impact of human immunodeficiency virus on the severity of buruli ulcer disease: results of a retrospective study in cameroon.


ABSTRACT:

Background

Buruli ulcer is the third most common mycobacterial disease after tuberculosis and leprosy and is particularly frequent in rural West and Central Africa. However, the impact of HIV infection on BU severity and prevalence remains unclear.

Methods

This was a retrospective study of data collected at the Akonolinga District Hospital, Cameroon, from January 1, 2002 to March 27, 2013. Human immunodeficiency virus prevalence among BU patients was compared with regional HIV prevalence. Baseline characteristics of BU patients were compared between HIV-negative and HIV-positive patients and according to CD4 cell count strata in the latter group. Buruli ulcer time-to-healing was assessed in different CD4 count strata, and factors associated with BU main lesion size at baseli

SUBMITTER: Christinet V 

PROVIDER: S-EPMC4324202 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature