Measurement of T₁ relaxation time of osteochondral specimens using VFA-SWIFT.

ABSTRACT:

Purpose

To evaluate the feasibility of SWIFT with variable flip angle (VFA) for measurement of T₁ relaxation time in Gd-agarose-phantoms and osteochondral specimens, including regions of very short T₂ *, and compare with T₁ measured using standard methods METHODS: T₁ s of agarose phantoms with variable concentration of Gd-DTPA^2- and nine pairs of native and trypsin-treated bovine cartilage-bone specimens were measured. For specimens, VFA-SWIFT, inversion recovery (IR) fast spin echo (FSE) and saturation recovery FSE were used. For phantoms, additionally spectroscopic IR was used. Differences and agreement between the methods were assessed using nonparametric Wilcoxon and Kruskal-Wallis tests and intraclass correlation.

Resul

SUBMITTER: Nissi MJ 

PROVIDER: S-EPMC4324366 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature