The immediate global responses of Aliivibrio salmonicida to iron limitations.

ABSTRACT:

Background

Iron is an essential micronutrient for all living organisms, and virulence and sequestration of iron in pathogenic bacteria are believed to be correlated. As a defence mechanism, potential hosts therefore keep the level of free iron inside the body to a minimum. In general, iron metabolism is well studied for some bacteria (mostly human or animal pathogens). However, this area is still under-investigated for a number of important bacterial pathogens. Aliivibrio salmonicida is a fish pathogen, and previous studies of this bacterium have shown that production of siderophores is temperature regulated and dependent on low iron conditions. In this work we studied the immediate changes in transcription in response to a sudden decrease in iron levels in cultures of A. salmonici

SUBMITTER: Thode SK 

PROVIDER: S-EPMC4324432 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature