Functional status at 18 months of age as a predictor of childhood disability after neonatal hypoxic-ischemic encephalopathy.

ABSTRACT:

Aim

In children with neonatal hypoxic-ischemic encephalopathy (HIE), we examined the association between 18-month functional status by parental report and disability at 6-7 years.

Method

Prospective observational study involving participants in the NICHD randomized controlled trial of hypothermia for HIE. Parent questionnaires-Functional Status-II (FS-II), Impact on Family (IOF) and Family Resource Scale (FRS) at 18 months were correlated with 6- to 7-year developmental assessments. Disability at 6-7 years was defined as IQ < 70, gross motor functional classification scale level III-V, bilateral blindness, deafness, or epilepsy.

Results

Rates of severe HIE (32 vs. 15%), public insurance (73% vs. 47%) and IOF scales were higher and mean (SD) FS-II independence (I) {54

SUBMITTER: Natarajan G 

PROVIDER: S-EPMC4324462 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature