The influence of different fever definitions on the rate of fever in neutropenia diagnosed in children with cancer.

ABSTRACT:

Background

The temperature limit defining fever (TLDF) is based on scarce evidence. This study aimed to determine the rate of fever in neutropenia (FN) episodes additionally diagnosed by lower versus standard TLDF.

Methods

In a single center using a high TLDF (39.0°C tympanic temperature, LimitStandard), pediatric patients treated with chemotherapy for cancer were observed prospectively. Results of all temperature measurements and CBCs were recorded. The application of lower TLDFs (LimitLow; range, 37.5°C to 38.9°C) versus LimitStandard was simulated in silicon, resulting in three types of FN: simultaneous FN, diagnosed at both limits within 1 hour; earlier FN, diagnosed >1hour earlier at LimitLow; and additional FN, not diagnosed at LimitStandard.

Results

In 39 patie

SUBMITTER: Ammann RA 

PROVIDER: S-EPMC4324993 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature