Active and passive smoking in relation to lung cancer incidence in the Women's Health Initiative Observational Study prospective cohort.

ABSTRACT:

Background

Lung cancer is the leading cause of worldwide cancer deaths. While smoking is its leading risk factor, few prospective cohort studies have reported on the association of lung cancer with both active and passive smoking. This study aimed to determine the relationship between lung cancer incidence with both active and passive smoking (childhood, adult at home, and at work).

Patients and methods

The Women's Health Initiative Observational Study (WHI-OS) was a prospective cohort study conducted at 40 US centers that enrolled postmenopausal women from 1993 to 1999. Among 93 676 multiethnic participants aged 50-79, 76 304 women with complete smoking and covariate data comprised the analytic cohort. Lung cancer incidence was calculated by Cox proportional hazards models,

SUBMITTER: Wang A 

PROVIDER: S-EPMC4326306 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature