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Four New Sesquiterpenoids from Cultures of the Fungus Phellinidium sulphurascens.

ABSTRACT: Four new sesquiterpenoids, namely 12-hydroxy-3-oxodrimenol (1), 11-hydroxyacetoxydrim-7-en-3β-ol (2), 2,6-dimethyl-7,10-epoxy-10-hydroxymethyldodeca-2,11-dien-6-ol (3), and 7,10-epoxy-2,6,10-trimethyldodeca-2,11-diene-4,6-diol (4), along with fourteen known compounds, were isolated from the cultures of Phellinidium sulphurascens. The structures of compounds 1-4 were established on the basis of extensive spectroscopic analysis. All of them were evaluated for their cytotoxic activities.

SUBMITTER: Zhao ZZ

PROVIDER: S-EPMC4328000 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature

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Four New Sesquiterpenoids from Cultures of the Fungus Phellinidium sulphurascens.

Zhao Zhen-Zhu ZZ Chen He-Ping HP Feng Tao T Li Zheng-Hui ZH Dong Ze-Jun ZJ Liu Ji-Kai JK

Natural products and bioprospecting 20141210

Four new sesquiterpenoids, namely 12-hydroxy-3-oxodrimenol (1), 11-hydroxyacetoxydrim-7-en-3β-ol (2), 2,6-dimethyl-7,10-epoxy-10-hydroxymethyldodeca-2,11-dien-6-ol (3), and 7,10-epoxy-2,6,10-trimethyldodeca-2,11-diene-4,6-diol (4), along with fourteen known compounds, were isolated from the cultures of Phellinidium sulphurascens. The structures of compounds 1-4 were established on the basis of extensive spectroscopic analysis. All of them were evaluated for their cytotoxic activities. ...[more]

PMID: 25491089

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