The characteristics of recurrent upper tract urothelial carcinoma after radical nephroureterectomy without bladder cuff excision.

ABSTRACT:

Purpose

To investigate oncological outcomes based on bladder cuff excision (BCE) during radical nephroureterectomy (RNU) for upper tract urothelial carcinoma (UTUC) and to provide clinical evidence of tumor recurrence in patients without BCE.

Materials and methods

We retrospectively collected data of 372 consecutive patients who underwent RNU at our institution from May 1989 through October 2010. After excluding some data, we reviewed 336 patients for the analysis.

Results

Of the patients who underwent RNU with BCE (n=279, 83.0%) and without BCE (n=57, 17.0%), patients without BCE had poorer cancer-specific and overall survival rates. Among 57 patients without BCE, 35 (61.4%) experienced tumor recurrence. Recurrence at the remnant ureter resulted in poor oncological o

SUBMITTER: Kang M 

PROVIDER: S-EPMC4329347 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature