Comparison of True and Smoothed Puff Profile Replication on Smoking Behavior and Mainstream Smoke Emissions.

ABSTRACT: To estimate exposures to smokers from cigarettes, smoking topography is typically measured and programmed into a smoking machine to mimic human smoking, and the resulting smoke emissions are tested for relative levels of harmful constituents. However, using only the summary puff data--with a fixed puff frequency, volume, and duration--may underestimate or overestimate actual exposure to smoke toxins. In this laboratory study, we used a topography-driven smoking machine that faithfully reproduces a human smoking session and individual human topography data (n = 24) collected during previous clinical research to investigate if replicating the true puff profile (TP) versus the mathematically derived smoothed puff profile (SM) resulted in differences in particle size distributions and selected

SUBMITTER: Brinkman MC 

PROVIDER: S-EPMC4332039 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature