Quantifying and monitoring overdiagnosis in cancer screening: a systematic review of methods.

ABSTRACT:

Objective

To determine the optimal method for quantifying and monitoring overdiagnosis in cancer screening over time.

Design

Systematic review of primary research studies of any design that quantified overdiagnosis from screening for nine types of cancer. We used explicit criteria to critically appraise individual studies and assess strength of the body of evidence for each study design (double blinded review), and assessed the potential for each study design to accurately quantify and monitor overdiagnosis over time.

Data sources

PubMed and Embase up to 28 February 2014; hand searching of systematic reviews.

Eligibility criteria for selecting studies

English language studies of any design that quantified overdiagnosis for any of nine common cancers (prostate,

SUBMITTER: Carter JL 

PROVIDER: S-EPMC4332263 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature