Heuristic exploitation of genetic structure in marker-assisted gene pyramiding problems.

ABSTRACT:

Background

Over the last decade genetic marker-based plant breeding strategies have gained increasing attention because genotyping technologies are no longer limiting. Now the challenge is to optimally use genetic markers in practical breeding schemes. For simple traits such as some disease resistances it is possible to target a fixed multi-locus allele configuration at a small number of causal or linked loci. Efficiently obtaining this genetic ideotype from a given set of parental genotypes is known as the marker-assisted gene pyramiding problem. Previous methods either imposed strong restrictions or used black box integer programming solutions, while this paper explores the power of an explicit heuristic approach that exploits the underlying genetic structure to prune the search

SUBMITTER: De Beukelaer H 

PROVIDER: S-EPMC4332449 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature