Association of sex hormones with sexual function, vitality, and physical function of symptomatic older men with low testosterone levels at baseline in the testosterone trials.

ABSTRACT:

Context

The prevalence of sexual dysfunction, low vitality, and poor physical function increases with aging, as does the prevalence of low total and free testosterone (TT and FT) levels. However, the relationship between sex hormones and age-related alterations in older men is not clear.

Objective

To test the hypotheses that baseline serum TT, FT, estradiol (E2), and sex hormone-binding globulin (SHBG) levels are independently associated with sexual function, vitality, and physical function in older symptomatic men with low testosterone levels participating in the Testosterone Trials (TTrials).

Design

Cross-sectional study of baseline measures in the TTrials.

Setting

The study was conducted at 12 sites in the United States.

Participants

The 788 TTrials p

SUBMITTER: Cunningham GR 

PROVIDER: S-EPMC4333035 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature