The posteromedial region of the default mode network shows attenuated task-induced deactivation in psychopathic prisoners.

ABSTRACT:

Objective

Psychopathy is a personality disorder with symptoms that include lack of empathy or remorse, antisocial behavior, and excessive self-focus. Previous neuroimaging studies have linked psychopathy to dysfunction in the default mode network (DMN), a brain network that deactivates during externally focused tasks and is more engaged during self-referential processing. Specifically, the DMN has been found to remain relatively active in individuals with psychopathic tendencies during externally focused tasks, suggesting a failure to properly deactivate. However, the exact extent and nature of task-induced DMN dysfunction is poorly understood, including (a) the degree to which specific DMN subregions are affected in criminal psychopaths, and (b) how activity in these subregions re

SUBMITTER: Freeman SM 

PROVIDER: S-EPMC4333113 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature