The impact of age on changes in quality of life among breast cancer survivors treated with breast-conserving surgery and radiotherapy.

ABSTRACT:

Background

The purpose of the study was to determine the impact of young age on health-related quality of life (HRQoL) by comparing HRQoL of younger and older breast cancer patients, corrected for confounding, and of young patients and a general Dutch population.

Methods

The population consisted of breast cancer survivors (stage 0-III) after breast-conserving surgery and radiotherapy. Health-related quality of life was prospectively assessed using the EORTC QLQ-C30 and QLQ-BR23 questionnaires. The association between age (⩽50; 51-70; ⩾70 years) and HRQoL over time was analysed with mixed modelling. The clinical relevance of differences between/within age groups was estimated with Cohen's D and consensus-based guidelines. The HRQoL data from the young patient cohort were comp

SUBMITTER: Bantema-Joppe EJ 

PROVIDER: S-EPMC4333491 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature