Resting-state temporal synchronization networks emerge from connectivity topology and heterogeneity.

ABSTRACT: Spatial patterns of coherent activity across different brain areas have been identified during the resting-state fluctuations of the brain. However, recent studies indicate that resting-state activity is not stationary, but shows complex temporal dynamics. We were interested in the spatiotemporal dynamics of the phase interactions among resting-state fMRI BOLD signals from human subjects. We found that the global phase synchrony of the BOLD signals evolves on a characteristic ultra-slow (<0.01Hz) time scale, and that its temporal variations reflect the transient formation and dissolution of multiple communities of synchronized brain regions. Synchronized communities reoccurred intermittently in time and across scanning sessions. We found that the synchronization communities relate to previ

SUBMITTER: Ponce-Alvarez A 

PROVIDER: S-EPMC4333573 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature